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Fundamentals of Separations

Separation Science

Separation Science

A series of collaborative learning activities and accompanying text that develop the field of separation science, with a particular emphasis on chromatographic separations, is provided. These activities are intended to be done in class by students working in groups, but can be modified for use as out-of-class exercises. Learning objectives, an instructor’s manual, and out-of-class problems…

Chromatography: Basic Concepts

Students explore basic aspects of chromatographic separations including concepts such as number of theoretical plates, separation factor, retention factor and resolution. There is an associated text that explains the answers to the questions on the worksheet.

Introduction to Chromatography

Introduction This learning module provides an interactive introduction to chromatography with an emphasis on understanding basic chromatographic terms and measurements, and on understanding the factors that affect the quality of a separation. The treatment is independent of the form of chromatography and, although data from GC and HPLC experiments are used to illustrate topics presented in…

Sample Preparation

Introduction This module introduces students to the topic of sample preparation using a variety of real-world examples from pharmaceutical analysis to environmental analysis. Liquid-liquid extraction, solid phase extraction, QuEChERS, derivatization in chromatography and solid-phase microextraction methods are discussed in a discovery-based and contextual manner. Table of Contents Introduction to Sample Preparation (Word)…
Interpreting primary literature

Interpreting the Primary Literature

Introduction These assignments are designed to be capstone activities at the end of units on figures of merit (such as sensitivity and LOD), acid-base equilibria, separations, spectroscopy, mass spectrometry, and electrochemistry. Each assignment consists of an out-of-class reading assignment drawn from the primary literature accompanied by objective questions and a set of open-ended, in-class discussion questions.…