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Mass Spectrometry

Mass Spectrometry

Introduction A series of collaborative learning activities and accompanying text that develop fundamental aspects of mass spectrometry. These activities are intended to be done in class by students working in groups, but can be modified for use as out-of-class exercises. Learning objectives are provided as well. In addition to some basic concepts of mass spectrometry, the…

Introduction to Mass Spectrometry

Introduction to Mass SpectrometryDownload After completing this activity, students will be able to: describe the relationship between the peak height in the mass spectrum and the natural abundance of isotopes differentiate between average mass, isotopic mass and nominal mass; identify the appropriate use of each in the analysis of mass spectrometric data identify the molecular ion…

Environmental Analysis – Lake Nakuru Flamingos: Pesticides

Could toxic pesticides like DDT be responsible for the deaths of large numbers of lesser flamingos at Lake Nakuru, Kenya? While many organochlorine pesticides including DDT have been banned for decades in the US due to their adverse effects on bird populations, especially bald eagles, they are still used for mosquito control in tropical regions of…

Mass Spectrometry: Performance Enhancing Drugs

Mass Spectrometry Performance Enhancing DrugsDownload After completing this activity, students will be able to: Identify the individual components of the MS and their respective functions. Describe how ions of different m/z are distinguished in a MS. Compare and contrast the capabilities of TOF and quadrupole MS detectors. Compare, and explain molecular fragmentation patterns. Use isotopic abundances and…
Interpreting primary literature

Interpreting the Primary Literature

Introduction These assignments are designed to be capstone activities at the end of units on figures of merit (such as sensitivity and LOD), acid-base equilibria, separations, spectroscopy, mass spectrometry, and electrochemistry. Each assignment consists of an out-of-class reading assignment drawn from the primary literature accompanied by objective questions and a set of open-ended, in-class discussion questions.…