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Sample Introduction in Gas Chromatography

After completing this activity, students will be able to:

  • Describe the operational principle of different entry-level techniques such as split/splitless, on column, PTV, thermal desorption-pyrolysis, purge and trap
  • Differentiate various types of GC sample introduction methods and determine their suitability for specific analytes in different matrices
  • Interpret the impact of sample introduction on a GC column (particularly on a capillary system) and on the resulting chromatogram from a perspective of how resolution and response for splitless and split injection would be affected.

Alena Kubatova, University of North Dakota (